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Non-malignant breast papillary lesions - b3 diagnosed on ultrasound--guided 14-gauge needle core biopsy: analysis of 114 cases from a single institution and review of the literature.
- Source :
-
Pathology oncology research : POR [Pathol Oncol Res] 2015 Jul; Vol. 21 (3), pp. 535-46. Date of Electronic Publication: 2015 Jan 10. - Publication Year :
- 2015
-
Abstract
- One-hundred-fourteen consecutive cases of breast ultrasound-guided 14-gauge needle core biopsy (14G NCB) performed from January 2001 to June 2013 and diagnosed as non-malignant papillary lesion (PL)-B3, were reviewed and compared with definitive histological diagnosis on surgical excision (SE) to evaluate the diagnostic accuracy of ultrasound-guided 14G NCB. PL with epithelial atypia on 14G NCB were associated to malignancy on definitive histological diagnosis on SE in 22 (7 DCIS and 15 invasive carcinomas) of 46 cases with an underestimation rate of 47.8 %, while 9 (4 DCIS and 5 invasive carcinomas) cases out of 68 cases of PL without epithelial atypia were upgraded to carcinoma with an underestimation rate of 13.2 %. In cases of PL with epithelial atypia on ultrasound-guided 14G NCB, SE appears mandatory due to the high risk of associated malignancy. The diagnosis of PL without epithelial atypia on ultrasound-guided 14G NCB does not exclude malignancy at subsequent SE, consequently further assessment (by surgical or vacuum-assisted excision) is recommended to avoid the risk of delaying a diagnosis of malignancy, although this tends to be lower (1 in 8 patients).
- Subjects :
- Adult
Aged
Biopsy
Breast Diseases diagnostic imaging
Breast Diseases surgery
Carcinoma, Ductal, Breast diagnostic imaging
Carcinoma, Ductal, Breast surgery
Carcinoma, Intraductal, Noninfiltrating diagnostic imaging
Carcinoma, Intraductal, Noninfiltrating surgery
Carcinoma, Papillary diagnostic imaging
Carcinoma, Papillary surgery
Female
Humans
Middle Aged
Neoplasm Staging
Prognosis
Retrospective Studies
Breast pathology
Breast Diseases pathology
Carcinoma, Ductal, Breast pathology
Carcinoma, Intraductal, Noninfiltrating pathology
Carcinoma, Papillary pathology
Ultrasonography, Interventional
Subjects
Details
- Language :
- English
- ISSN :
- 1532-2807
- Volume :
- 21
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Pathology oncology research : POR
- Publication Type :
- Academic Journal
- Accession number :
- 25573591
- Full Text :
- https://doi.org/10.1007/s12253-014-9882-7