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Chemical constituents, anticancer, antimicrobial and antioxidant activities of essential oil from Anaphalis lacteal grown in Qinghai-Tibet Plateau.
- Source :
-
Natural product research [Nat Prod Res] 2015; Vol. 29 (14), pp. 1369-71. Date of Electronic Publication: 2015 Jan 08. - Publication Year :
- 2015
-
Abstract
- The chemical constituent of the essential oil from Anaphalis lacteal was determined; 31 compounds, representing 93.91% of the total oil, were identified by gas chromatography-mass spectrometry analysis. Three Gram-positive bacteria species, three Gram-negative bacteria species and four fungi were used to determine antimicrobial activity; the results revealed that the essential oil had a remarkable antimicrobial effect against bacteria and a susceptive effect against fungus. The oil also possessed more efficient free-radical scavenging activities than butylated hydroxytoluene (BHT) with 50% inhibitory concentration (IC50) value 31 μg/mL (40 μg/mL for BHT). MTT assay illustrated that the oil expressed certain effect in inhibiting the growth of HeLa and Hep-6 cancer cells.
- Subjects :
- Cell Line, Tumor drug effects
China
Fungi drug effects
Gram-Negative Bacteria drug effects
Gram-Positive Bacteria drug effects
Humans
Inhibitory Concentration 50
Microbial Sensitivity Tests
Tibet
Anti-Infective Agents chemistry
Antineoplastic Agents, Phytogenic chemistry
Antioxidants chemistry
Asteraceae chemistry
Oils, Volatile chemistry
Plant Oils chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1478-6427
- Volume :
- 29
- Issue :
- 14
- Database :
- MEDLINE
- Journal :
- Natural product research
- Publication Type :
- Academic Journal
- Accession number :
- 25566798
- Full Text :
- https://doi.org/10.1080/14786419.2014.997728