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Craniofacial and pharyngeal airway morphology in patients with acromegaly.
- Source :
-
Acta odontologica Scandinavica [Acta Odontol Scand] 2015 Aug; Vol. 73 (6), pp. 433-40. Date of Electronic Publication: 2014 Dec 29. - Publication Year :
- 2015
-
Abstract
- Objective: The aim of this study was to assess differences in craniofacial characteristics, upper spine and pharyngeal airway morphology in patients with acromegaly compared with healthy individuals.<br />Materials and Methods: Twenty-one patients with acromegaly were compared with 22 controls by linear and angular measurements on cephalograms. The differences between the mean values of cephalometric parameters were analyzed with Mann-Whitney U-test.<br />Results: With respect to controls, anterior (p<0.05), middle (p<0.01) and posterior (p<0.05) cranial base lengths were increased, sella turcica was enlarged (p<0.001) and upper spine morphology demonstrated differences in the height of atlas (p<0.01) and axis (p<0.05) in patients with acromegaly. Craniofacial changes were predominantly found in the frontal bone (p<0.01) and the mandible (p<0.05). As for the airway, patients with acromegaly exhibited diminished dimensions at nasal (p<0.001), uvular (p<0.01), mandibular (p<0.01) pharyngeal levels and at the narrowest point of the pharyngeal airway space (p<0.001) compared to healthy controls. Soft palate width was significantly higher (p<0.001) and the hyoid bone was more vertically positioned (p<0.01) in patients with acromegaly.<br />Conclusions: Current results point to the importance of the reduced airway dimensions and that dentists and/or orthodontists should be aware of the cranial or dental abnormalities in patients with acromegaly.
- Subjects :
- Adult
Axis, Cervical Vertebra pathology
Cephalometry methods
Cervical Atlas pathology
Female
Frontal Bone pathology
Humans
Hyoid Bone pathology
Male
Mandible pathology
Middle Aged
Nasal Bone pathology
Palate, Soft pathology
Sella Turcica pathology
Skull Base pathology
Uvula pathology
Young Adult
Acromegaly pathology
Facial Bones pathology
Pharynx pathology
Skull pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1502-3850
- Volume :
- 73
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Acta odontologica Scandinavica
- Publication Type :
- Academic Journal
- Accession number :
- 25543455
- Full Text :
- https://doi.org/10.3109/00016357.2014.979868