[The characteristics of [3H]muscimol binding to the synaptic membranes of the cerebral cortex in the progeny of rats subjected to deprivation of the paradoxical sleep phase during pregnancy].

Authors :: Zhulin VV
Zabludovskiĭ AL
Source :: Nauchnye doklady vysshei shkoly. Biologicheskie nauki [Nauchnye Doki Vyss Shkoly Biol Nauki] 1989 (6), pp. 54-6.
Publication Year :: 1989
Abstract: White rats were subjected to REM-sleep deprivation during 14-20 days of pregnancy. [3H]muscimol binding level of neocortex synaptosomal membranes was significantly higher in their offsprings as compared with the control ones. Possible ways of GABA-ergic system malformations are discussed.

Subjects :: Animals
Cerebral Cortex analysis
Female
Muscimol analysis
Pregnancy
Rats
Receptors, GABA-A analysis
Receptors, GABA-A metabolism
Synaptic Membranes analysis
Tritium
Cerebral Cortex metabolism
Muscimol metabolism
Prenatal Exposure Delayed Effects
Sleep Deprivation physiology
Sleep, REM physiology
Synaptic Membranes metabolism

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