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Centriole duplication: when PLK4 meets Ana2/STIL.
- Source :
-
Current biology : CB [Curr Biol] 2014 Nov 03; Vol. 24 (21), pp. R1046-8. Date of Electronic Publication: 2014 Nov 03. - Publication Year :
- 2014
-
Abstract
- Polo-like kinase 4 is known to drive centriole duplication, but the relevant substrate remains elusive. A new study shows that PLK4 phosphorylates a key centriolar component, Ana2/STIL, to initiate centriole assembly.<br /> (Copyright © 2014 Elsevier Ltd. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1879-0445
- Volume :
- 24
- Issue :
- 21
- Database :
- MEDLINE
- Journal :
- Current biology : CB
- Publication Type :
- Academic Journal
- Accession number :
- 25517369
- Full Text :
- https://doi.org/10.1016/j.cub.2014.09.079