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Association between DLK1 and IGF-I gene expression and meat quality in sheep.
- Source :
-
Genetics and molecular research : GMR [Genet Mol Res] 2014 Dec 04; Vol. 13 (4), pp. 10308-19. Date of Electronic Publication: 2014 Dec 04. - Publication Year :
- 2014
-
Abstract
- The aim of the present study was to detect delta-like 1 ho-molog (DLK1) and insulin-like growth factor-I (IGF-I) gene expression in the longissimus dorsi of Hu sheep at different growth stages and study the association between these genes and meat quality. The diameter and density of muscle fibers and tenderness of the longissimus dorsi were measured. Growth stage, but not sex, significantly affected DLK1 and IGF-I expression. DLK1 and IGF-I expression in the sheep longissimus dorsi gradually increased with growth, but also decreased during some periods. These results suggest that different growth stages significantly affect DLK1 and IGF-I gene expression in sheep muscle tissue. The ex-pression of DLK1 and IGF-I genes were positively and significantly (P < 0.01) correlated with muscle fiber diameter and muscle fiber shear stress, and negatively and significantly (P < 0.01) correlated with muscle fiber density. Muscle fiber diameter was positively and significantly (P < 0.01) correlated with muscle fiber shear stress, and negatively and significantly (P < 0.01) correlated with muscle fiber density. In addition, DLK-1 expression was significantly (P < 0.01) and positively correlated with IGF-I expression.
- Subjects :
- Animals
Gene Expression
Insulin-Like Growth Factor I genetics
Muscle, Skeletal metabolism
Sheep, Domestic growth & development
Insulin-Like Growth Factor I biosynthesis
Intercellular Signaling Peptides and Proteins biosynthesis
Meat
Membrane Proteins biosynthesis
Muscle Fibers, Slow-Twitch metabolism
Sheep, Domestic genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1676-5680
- Volume :
- 13
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Genetics and molecular research : GMR
- Publication Type :
- Academic Journal
- Accession number :
- 25501243
- Full Text :
- https://doi.org/10.4238/2014.December.4.26