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Taking charge of siRNA delivery.

Authors :
Khvorova A
Osborn MF
Hassler MR
Source :
Nature biotechnology [Nat Biotechnol] 2014 Dec; Vol. 32 (12), pp. 1197-8.
Publication Year :
2014

Abstract

Delivery of siRNA into cells is achieved by neutralizing the negative charge of the phosphate backbone in a reversible manner.

Details

Language :
English
ISSN :
1546-1696
Volume :
32
Issue :
12
Database :
MEDLINE
Journal :
Nature biotechnology
Publication Type :
Academic Journal
Accession number :
25489835
Full Text :
https://doi.org/10.1038/nbt.3091