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Splenic and hepatic ultrasound and cytology in canine lymphoma: effects of findings on stage migration and assessment of prognosis.
- Source :
-
Veterinary and comparative oncology [Vet Comp Oncol] 2016 Aug; Vol. 14 Suppl 1, pp. 82-94. Date of Electronic Publication: 2014 Dec 03. - Publication Year :
- 2016
-
Abstract
- Stage migration is described in humans and dogs as a sequel of using more sensitive diagnostic methods. One hundred eighty-six dogs with multicentric lymphoma were enrolled with results of conventional staging as well as ultrasonographic and cytological examination of liver and spleen being available. The addition of splenic respective hepatic ultrasound and cytology findings resulted in slightly lower number of dogs classified as having liver and spleen involvement. In dogs with multicentric lymphoma, addition of cytology led to a significant shift of individuals from stage IV to stage III. Findings of hepatic and splenic ultrasound and cytology exerted no significant influence on complete remission and survival durations in dogs with combination chemotherapy. Staging methodology in canine lymphoma should be redefined, considering that the prognostic significance of splenic and hepatic ultrasound and cytology warrants further investigation.<br /> (© 2014 John Wiley & Sons Ltd.)
- Subjects :
- Animals
Dog Diseases diagnostic imaging
Dogs
Female
Immunophenotyping veterinary
Kaplan-Meier Estimate
Liver diagnostic imaging
Lymphoma, Non-Hodgkin diagnostic imaging
Lymphoma, Non-Hodgkin pathology
Male
Neoplasm Staging methods
Neoplasm Staging veterinary
Prognosis
Retrospective Studies
Spleen diagnostic imaging
Survival
Ultrasonography veterinary
Dog Diseases pathology
Liver pathology
Lymphoma, Non-Hodgkin veterinary
Spleen pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1476-5829
- Volume :
- 14 Suppl 1
- Database :
- MEDLINE
- Journal :
- Veterinary and comparative oncology
- Publication Type :
- Academic Journal
- Accession number :
- 25470748
- Full Text :
- https://doi.org/10.1111/vco.12127