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Sparse evidence of MERS-CoV infection among animal workers living in Southern Saudi Arabia during 2012.
- Source :
-
Influenza and other respiratory viruses [Influenza Other Respir Viruses] 2015 Mar; Vol. 9 (2), pp. 64-7. Date of Electronic Publication: 2014 Dec 03. - Publication Year :
- 2015
-
Abstract
- Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging viral pathogen that primarily causes respiratory illness. We conducted a seroprevalence study of banked human serum samples collected in 2012 from Southern Saudi Arabia. Sera from 300 animal workers (17% with daily camel exposure) and 50 non-animal-exposed controls were examined for serological evidence of MERS-CoV infection by a pseudoparticle MERS-CoV spike protein neutralization assay. None of the sera reproducibly neutralized the MERS-CoV-pseudotyped lentiviral vector. These data suggest that serological evidence of zoonotic transmission of MERS-CoV was not common among animal workers in Southern Saudi Arabia during July 2012.<br /> (© 2014 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.)
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Animals
Camelus
Coronavirus Infections immunology
Coronavirus Infections transmission
Female
Humans
Male
Middle Aged
Neutralization Tests
Saudi Arabia epidemiology
Seroepidemiologic Studies
Young Adult
Antibodies, Viral blood
Coronavirus Infections epidemiology
Middle East Respiratory Syndrome Coronavirus immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1750-2659
- Volume :
- 9
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Influenza and other respiratory viruses
- Publication Type :
- Academic Journal
- Accession number :
- 25470665
- Full Text :
- https://doi.org/10.1111/irv.12287