Moyamoya syndrome associated with Alagille syndrome: outcome after surgical revascularization.

Authors :: Baird LC
Smith ER
Ichord R
Piccoli DA
Bernard TJ
Spinner NB
Scott RM
Kamath BM
Source :: The Journal of pediatrics [J Pediatr] 2015 Feb; Vol. 166 (2), pp. 470-3. Date of Electronic Publication: 2014 Oct 30.
Publication Year :: 2015
Abstract: Vasculopathy is well-described in Alagille syndrome (ALGS); however, few data exist regarding neurosurgical interventions. We report 5 children with ALGS with moyamoya who underwent revascularization surgery. Postsurgical complications included 1 stroke and 1 death from thalamic hemorrhage. Global function improved in survivors. Revascularization is reasonably safe in patients with ALGS and may improve neurologic outcomes.<br /> (Copyright © 2015 Elsevier Inc. All rights reserved.)

Subjects :: Child, Preschool
Female
Humans
Infant
Male
Retrospective Studies
Treatment Outcome
Alagille Syndrome complications
Cerebral Revascularization
Moyamoya Disease etiology
Moyamoya Disease surgery

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