Inflammatory breast cancer: an overview.

Authors :: van Uden DJ
van Laarhoven HW
Westenberg AH
de Wilt JH
Blanken-Peeters CF
Source :: Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2015 Feb; Vol. 93 (2), pp. 116-26. Date of Electronic Publication: 2014 Oct 16.
Publication Year :: 2015
Abstract: Inflammatory breast cancer (IBC) is the most aggressive entity of breast cancer. Management involves coordination of multidisciplinary management and usually includes neoadjuvant chemotherapy, ablative surgery if a tumor-free resection margin is expected and locoregional radiotherapy. This multimodal therapeutic approach has significantly improved patient survival. However, the median overall survival among women with IBC is still poor. By elucidating the biologic characteristics of IBC, new treatment options may become available. We performed a comprehensive review of the English-language literature on IBC through computerized literature searches. The objective of the current review is to present an overview of the literature related to the biology, imaging and multidisciplinary treatment of inflammatory breast cancer.<br /> (Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.)