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[Therapy of intermediate uveitis].

Authors :
Doycheva D
Deuter C
Zierhut M
Source :
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft [Ophthalmologe] 2014 Dec; Vol. 111 (12), pp. 1219-32; quiz 1233-4.
Publication Year :
2014

Abstract

Intermediate uveitis is a form of intraocular inflammation in which the vitreous body is the major site of inflammation. Intermediate uveitis is primarily treated medicinally and systemic corticosteroids are the mainstay of therapy. When recurrence of uveitis or side effects occur during corticosteroid therapy an immunosuppressive treatment is required. Cyclosporine A is the only immunosuppressive agent that is approved for therapy of uveitis in Germany; however, other immunosuppressive drugs have also been shown to be effective and well-tolerated in patients with intermediate uveitis. In severe therapy-refractory cases when conventional immunosuppressive therapy has failed, biologics can be used. In patients with unilateral uveitis or when the systemic therapy is contraindicated because of side effects, an intravitreal steroid treatment can be carried out. In certain cases a vitrectomy may be used.

Details

Language :
German
ISSN :
1433-0423
Volume :
111
Issue :
12
Database :
MEDLINE
Journal :
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Publication Type :
Academic Journal
Accession number :
25448321
Full Text :
https://doi.org/10.1007/s00347-014-3201-2