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Insertion sequence elements in Lactococcus garvieae.
- Source :
-
Gene [Gene] 2015 Jan 25; Vol. 555 (2), pp. 291-6. Date of Electronic Publication: 2014 Nov 13. - Publication Year :
- 2015
-
Abstract
- Insertion sequences are the simplest intracellular Mobile Genetic Elements which can occur in very high numbers in prokaryotic genomes, where they play an important evolutionary role by promoting genome plasticity. As such, the studies on the diversity and distribution of insertion sequences in genomes not yet investigated can contribute to improve the knowledge on a bacterial species and to identify new transposable elements. The present work describes the occurrence of insertion sequences in Lactococcus garvieae, an opportunistic emerging zoonotic and human pathogen, also associated with different food matrices. To date, no insertion elements have been described for L. garvieae in the IS element database. The analysis of the twelve published L. garvieae genomes identified 15 distinct insertion sequences that are members of the IS3, IS982, IS6, IS21 and IS256 families, including five new elements. Most of the insertion sequences in L. garvieae show substantial homology to the Lactococcus lactis elements, suggesting the movement of IS between these two species phylogenetically closely related. ISLL6 elements belonging to IS3 family were most abundant, with several copies distributed in 9 of the 12 genomes analyzed. An alignment analysis of two complete genomes carrying multi-copies of this insertion sequence indicates a possible involvement of ISLL6 in chromosomal rearrangement.<br /> (Copyright © 2014 Elsevier B.V. All rights reserved.)
- Subjects :
- Base Sequence
Gene Transfer, Horizontal
Genome, Bacterial
Humans
Lactococcus lactis genetics
Molecular Sequence Data
Open Reading Frames
Phylogeny
Repetitive Sequences, Nucleic Acid
Sequence Alignment
Sequence Analysis, DNA
DNA Transposable Elements
Lactococcus genetics
Streptococcal Infections microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 1879-0038
- Volume :
- 555
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Gene
- Publication Type :
- Academic Journal
- Accession number :
- 25447909
- Full Text :
- https://doi.org/10.1016/j.gene.2014.11.019