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[Peripheral neuropathy and cyclosporin. Apropos of 2 cases].

Authors :
Blin O
Desnuelle C
Pellissier JF
Pouget J
Serratrice G
Vialettes B
Bory M
Source :
Therapie [Therapie] 1989 Jan-Feb; Vol. 44 (1), pp. 55-7.
Publication Year :
1989

Abstract

We report two cases of peripheral neuropathy arose during treatment with cyclosporine. The first observation was in a 24 year-old female treated because of a recent diabetes mellitus, the second in a 52 year-old male whose treatment was given after a cardiac transplantation. Chronology, clinical presentation and morphological findings on nerve biopsy were very close in both cases ans intrinsic imputability was stated as "possible" according to the method used to assess unexpected or toxic drug reaction by the French Regional Drug Monitoring Centers. It remains to confirm with similar reports the putative part played by cyclosporine as strongly suggested in ours.

Details

Language :
French
ISSN :
0040-5957
Volume :
44
Issue :
1
Database :
MEDLINE
Journal :
Therapie
Publication Type :
Academic Journal
Accession number :
2544035