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The genetics of diabetic pregnancy.
- Source :
-
Best practice & research. Clinical obstetrics & gynaecology [Best Pract Res Clin Obstet Gynaecol] 2015 Jan; Vol. 29 (1), pp. 102-9. Date of Electronic Publication: 2014 Aug 26. - Publication Year :
- 2015
-
Abstract
- Advancements in molecular technology coupled with a greater awareness of the human genome and epigenome have broadened our understanding of the genetic contributions to the diabetic pregnancy. There are multiple genes and pathways that can result in a hyperglycemic environment for the fetus. Exposure to this environment in utero has an impact on the risk of adult-onset chronic diseases. How identification of an individual's genetic variants will impact clinical care and outcomes will continue to evolve as our understanding grows.<br /> (Copyright © 2014 Elsevier Ltd. All rights reserved.)
- Subjects :
- Female
Genetic Markers
Humans
Hyperglycemia genetics
Mutation
Pregnancy
Diabetes Mellitus, Type 1 genetics
Diabetes Mellitus, Type 2 genetics
Diabetes, Gestational genetics
Epigenesis, Genetic
Genetic Predisposition to Disease
Pregnancy in Diabetics genetics
Prenatal Exposure Delayed Effects genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1532-1932
- Volume :
- 29
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Best practice & research. Clinical obstetrics & gynaecology
- Publication Type :
- Academic Journal
- Accession number :
- 25438929
- Full Text :
- https://doi.org/10.1016/j.bpobgyn.2014.08.008