Genomic dissection of travel-associated extended-spectrum-beta-lactamase-producing Salmonella enterica serovar typhi isolates originating from the Philippines: a one-off occurrence or a threat to effective treatment of typhoid fever?

Authors :: Hendriksen RS
Leekitcharoenphon P
Mikoleit M
Jensen JD
Kaas RS
Roer L
Joshi HB
Pornruangmong S
Pulsrikarn C
Gonzalez-Aviles GD
Reuland EA
Al Naiemi N
Wester AL
Aarestrup FM
Hasman H
Source :: Journal of clinical microbiology [J Clin Microbiol] 2015 Feb; Vol. 53 (2), pp. 677-80. Date of Electronic Publication: 2014 Nov 26.
Publication Year :: 2015
Abstract: One unreported case of extended-spectrum-beta-lactamase (ESBL)-producing Salmonella enterica serovar Typhi was identified, whole-genome sequence typed, among other analyses, and compared to other available genomes of S. Typhi. The reported strain was similar to a previously published strain harboring blaSHV-12 from the Philippines and likely part of an undetected outbreak, the first of ESBL-producing S. Typhi.<br /> (Copyright © 2015, American Society for Microbiology. All Rights Reserved.)

Subjects :: Disease Outbreaks
Genome, Bacterial
Genotype
Humans
Molecular Sequence Data
Philippines epidemiology
Salmonella typhi genetics
Sequence Analysis, DNA
Typhoid Fever epidemiology
beta-Lactamases genetics
Salmonella typhi enzymology
Salmonella typhi isolation & purification
Travel
Typhoid Fever microbiology
beta-Lactamases metabolism

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