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Malignant syphilis in an AIDS patient.
- Source :
-
Infection [Infection] 2015 Apr; Vol. 43 (2), pp. 231-6. Date of Electronic Publication: 2014 Nov 19. - Publication Year :
- 2015
-
Abstract
- Malignant syphilis is an uncommon, but not unknown, ulcerative variation of secondary syphilis. The lesions typically begin as papules, which quickly evolve to pustules and then to ulcers with elevated edges and central necrosis. It is usually, but not mandatory, found in patients with some level of immunosuppression, such as HIV patients, when the TCD4(+) cell count is >200 cells/mm(3). Despite the anxiety the lesions cause, this form of the disease has a good prognosis. The general symptoms disappear right after the beginning of treatment, and lesions disappear over a variable period. This study reports the case of a 27-year-old man who has been HIV positive for 6 years, uses antiretroviral therapy incorrectly, has a TCD4(+) cell count of 340 cells/mm(3), a VDRL of 1:128 and itchy disseminated hyperchromic maculopapular lesions with rupioid crusts compatible with malignant syphilis.
- Subjects :
- Acquired Immunodeficiency Syndrome drug therapy
Adult
Anti-Bacterial Agents therapeutic use
Antiretroviral Therapy, Highly Active
Homosexuality, Male
Humans
Male
Skin pathology
Syphilis drug therapy
Treatment Outcome
Acquired Immunodeficiency Syndrome diagnosis
Coinfection
Syphilis diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1439-0973
- Volume :
- 43
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Infection
- Publication Type :
- Academic Journal
- Accession number :
- 25408098
- Full Text :
- https://doi.org/10.1007/s15010-014-0698-x