Back to Search Start Over

Measurement of nitric oxide in mast cells with the fluorescent indicator DAF-FM diacetate.

Authors :
St Laurent CD
Moon TC
Befus AD
Source :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2015; Vol. 1220, pp. 339-45.
Publication Year :
2015

Abstract

The production of nitric oxide in mast cells has been difficult to measure due to the low amounts made by mast cells, as well as limitations in the specificity and sensitivity of the assays available. We present here a sensitive and specific 96-well plate-based method to directly measure NO using the cell-permeable fluorescent compound DAF-FM diacetate.

Details

Language :
English
ISSN :
1940-6029
Volume :
1220
Database :
MEDLINE
Journal :
Methods in molecular biology (Clifton, N.J.)
Publication Type :
Academic Journal
Accession number :
25388261
Full Text :
https://doi.org/10.1007/978-1-4939-1568-2_21