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Cytogenetic studies in 11 patients with small cell carcinoma of the lung.
- Source :
-
Mayo Clinic proceedings [Mayo Clin Proc] 1989 Feb; Vol. 64 (2), pp. 168-76. - Publication Year :
- 1989
-
Abstract
- Small cell carcinoma of the lung has reportedly been associated with structural abnormalities of the short arm of chromosome 3, but most of the previous studies were done on long-term cultures that involved cell lines. In the current study, we investigated the chromosome abnormalities in specimens from primary lung tumors grown in short-term cultures. Cytogenetic studies were done in 11 patients with small cell carcinoma of the lung, and a chromosomally abnormal clone was observed in each tumor. An abnormality of chromosome 3 was observed in six of these tumors.
Details
- Language :
- English
- ISSN :
- 0025-6196
- Volume :
- 64
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Mayo Clinic proceedings
- Publication Type :
- Academic Journal
- Accession number :
- 2537918
- Full Text :
- https://doi.org/10.1016/s0025-6196(12)65671-7