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Catalyst-free synthesis of highly biologically active 5-arylidene rhodanine and 2,4-thiazolidinedione derivatives using aldonitrones in polyethylene glycol.

Authors :
Kumar D
Narwal S
Sandhu JS
Source :
International journal of medicinal chemistry [Int J Med Chem] 2013; Vol. 2013, pp. 273534. Date of Electronic Publication: 2013 Feb 14.
Publication Year :
2013

Abstract

A green, efficient synthesis of 5-arylidene rhodanine and 2,4-thiazolidinedione derivatives without using any external catalyst in polyethylene glycol (PEG) at 80°C has been described. Reaction procedure is very simple, short, and obtained yields are very high.

Details

Language :
English
ISSN :
2090-2069
Volume :
2013
Database :
MEDLINE
Journal :
International journal of medicinal chemistry
Publication Type :
Academic Journal
Accession number :
25374689
Full Text :
https://doi.org/10.1155/2013/273534