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Bioaccumulation of BDE-47 and effects on molecular biomarkers acetylcholinesterase, glutathione-S-transferase and glutathione peroxidase in Mytilus galloprovincialis mussels.
- Source :
-
Ecotoxicology (London, England) [Ecotoxicology] 2015 Mar; Vol. 24 (2), pp. 292-300. Date of Electronic Publication: 2014 Nov 06. - Publication Year :
- 2015
-
Abstract
- Mussels, Mytilus galloprovincialis, showed a high bioaccumulation ability when exposed to waterborne tetrabromodiphenyl ether (BDE-47), with a bioconcentration factor of 10,900 L Kg(-1) wet weight, and slow depuration rates in clean seawater. Kinetic and concentration-response experiments were performed measuring in the exposed mussel the activities of three molecular biomarkers: glutathione S-transferase (GST), glutathione peroxidase (GPx) and acetylcholinesterase (AChE). The long term (30 days) exposure of mussels to all concentrations (2-15 µg L(-1)) of BDE-47 significantly inhibited the AChE and GST activities, a result that supports the suitability of these biomarkers in marine pollution monitoring programs. However, GPx activity showed a less consistent pattern of response depending on the concentration and the duration of exposure.
- Subjects :
- Acetylcholinesterase metabolism
Animals
Biomarkers metabolism
Environmental Monitoring
Glutathione Peroxidase metabolism
Glutathione Transferase metabolism
Mytilus enzymology
Spain
Water Pollutants, Chemical metabolism
Water Pollutants, Chemical pharmacology
Halogenated Diphenyl Ethers metabolism
Halogenated Diphenyl Ethers pharmacology
Mytilus drug effects
Subjects
Details
- Language :
- English
- ISSN :
- 1573-3017
- Volume :
- 24
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Ecotoxicology (London, England)
- Publication Type :
- Academic Journal
- Accession number :
- 25373544
- Full Text :
- https://doi.org/10.1007/s10646-014-1377-5