Field testing the ENSEMBLE Minimum Dataset: performance of an instrument to address heterogeneity of treatment effects.

Authors :: Brenneman SK
Shen W
Brekke L
Paczkowski R
Bancroft T
Kaplan SH
Greenfield S
Berger M
Buesching DP
Source :: Journal of comparative effectiveness research [J Comp Eff Res] 2014 Sep; Vol. 3 (5), pp. 463-72.
Publication Year :: 2014
Abstract: Aim: To assess the ability of ENterprising SElective Multi-instrument BLend for hEterogeneity analysis (ENSEMBLE) Minimum Dataset instrument dimensions to discriminate among subgroups of patients expected to have differential outcomes.<br />Materials & Methods: Patients with Type 2 diabetes, knee osteoarthritis, ischemic heart disease or heart failure completed a survey designed to represent three dimensions (health, personality and behavior). Health-related outcomes and utilization were investigated using claims data. Discriminant validity and associations between the dimensions and outcomes were assessed.<br />Results: A total of 2625 patients completed the survey. The dimensions discriminated 50-100% of the outcome levels across disease cohorts; behavior dimension scores did not differ significantly among the healthcare utilization level subgroups in any disease cohort.<br />Conclusion: ENSEMBLE Minimum Dataset dimensions discriminated health-related outcome levels among patients with varied diseases.

Subjects :: Comparative Effectiveness Research methods
Comparative Effectiveness Research statistics & numerical data
Cross-Sectional Studies
Female
Humans
Male
Middle Aged
Outcome and Process Assessment, Health Care statistics & numerical data
Reproducibility of Results
Retrospective Studies
Surveys and Questionnaires
Datasets as Topic standards
Diabetes Mellitus, Type 2 therapy
Heart Failure therapy
Myocardial Ischemia therapy
Osteoarthritis, Knee therapy
Outcome and Process Assessment, Health Care methods
Patient Outcome Assessment

Full Text Access

Tools