CATH: comprehensive structural and functional annotations for genome sequences.

Authors :: Sillitoe I
Lewis TE
Cuff A
Das S
Ashford P
Dawson NL
Furnham N
Laskowski RA
Lee D
Lees JG
Lehtinen S
Studer RA
Thornton J
Orengo CA
Source :: Nucleic acids research [Nucleic Acids Res] 2015 Jan; Vol. 43 (Database issue), pp. D376-81. Date of Electronic Publication: 2014 Oct 27.
Publication Year :: 2015
Abstract: The latest version of the CATH-Gene3D protein structure classification database (4.0, http://www.cathdb.info) provides annotations for over 235,000 protein domain structures and includes 25 million domain predictions. This article provides an update on the major developments in the 2 years since the last publication in this journal including: significant improvements to the predictive power of our functional families (FunFams); the release of our 'current' putative domain assignments (CATH-B); a new, strictly non-redundant data set of CATH domains suitable for homology benchmarking experiments (CATH-40) and a number of improvements to the web pages.<br /> (© The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.)