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Biomedical applications of holographic microspectroscopy [invited].

Biomedical applications of holographic microspectroscopy [invited].

Authors :
Jung J
Kim K
Yu H
Lee K
Lee S
Nahm S
Park H
Park Y
Source :
Applied optics [Appl Opt] 2014 Sep 20; Vol. 53 (27), pp. G111-22.
Publication Year :
2014

Abstract

The identification and quantification of specific molecules are crucial for studying the pathophysiology of cells, tissues, and organs as well as diagnosis and treatment of diseases. Recent advances in holographic microspectroscopy, based on quantitative phase imaging or optical coherence tomography techniques, show promise for label-free noninvasive optical detection and quantification of specific molecules in living cells and tissues (e.g., hemoglobin protein). To provide important insight into the potential employment of holographic spectroscopy techniques in biological research and for related practical applications, we review the principles of holographic microspectroscopy techniques and highlight recent studies.

Details

Language :
English
ISSN :
1539-4522
Volume :
53
Issue :
27
Database :
MEDLINE
Journal :
Applied optics
Publication Type :
Academic Journal
Accession number :
25322118
Full Text :
https://doi.org/10.1364/AO.53.00G111