Back to Search
Start Over
Renal artery stenosis in association with congenital anomalies of the kidney and urinary tract.
- Source :
-
Saudi medical journal [Saudi Med J] 2014 Oct; Vol. 35 (10), pp. 1264-6. - Publication Year :
- 2014
-
Abstract
- Objectives: To describe 8 cases of renal artery stenosis (RAS) in children with congenital anomalies of the renal tract.<br />Methods: We conducted a retrospective chart review of 78 children with RAS who were followed up at Great Ormond Street Hospital, London, United Kingdom between 2003 and 2012. We used an interventional radiology database to identify all patients who had RAS confirmed by digital subtraction angiography and examined all cases of congenital anomaly of the renal tract that had been diagnosed during childhood.<br />Results: We documented the following renal anomalies: multicystic dysplastic kidney (n=2), renal hypoplasia (n=1), congenital solitary kidney with hydronephrosis (n=1), and unilateral vesicoureteric reflux with poorly functioning kidneys (n=2). The anomaly was unknown in 2 cases. Seven children had unilateral nephrectomy at a median age of 2.5 years (range, 0.4-10 years) for various urological abnormalities. All children were confirmed to have RAS after presentation with hypertension at a median age of 10 (3.5-16.2) years. Angioplasty was performed in 7 children, of which 6 achieved control of their blood pressure on reduced medications.<br />Conclusion: We highlight the association between RAS and other renal anomalies, which indicates that they could share a common genetic background.
- Subjects :
- Adolescent
Angiography, Digital Subtraction
Child
Child, Preschool
Female
Humans
Hypertension etiology
Male
Renal Artery Obstruction complications
Renal Artery Obstruction diagnostic imaging
Retrospective Studies
Urinary Tract abnormalities
Urogenital Abnormalities complications
Angioplasty
Antihypertensive Agents therapeutic use
Hypertension therapy
Kidney abnormalities
Multicystic Dysplastic Kidney complications
Renal Artery Obstruction surgery
Vesico-Ureteral Reflux complications
Subjects
Details
- Language :
- English
- ISSN :
- 0379-5284
- Volume :
- 35
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Saudi medical journal
- Publication Type :
- Academic Journal
- Accession number :
- 25316474