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The disconnect between a national tuberculosis drug resistance survey and treatment outcomes: a lost opportunity.
- Source :
-
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease [Int J Tuberc Lung Dis] 2014 Nov; Vol. 18 (11), pp. 1319-22. - Publication Year :
- 2014
-
Abstract
- We linked results from the Fourth Botswana National Drug Resistance Survey (DRS), 2007-2008, to patient records from the national Electronic Tuberculosis Registry to determine treatment outcomes. Of 915 new patients, 651 (71%) had treatment data available. Completion or cure was achieved for 10/15 (67%, 95%CI 42-85) with isoniazid monoresistance, (6/16, 38%, 95%CI 18-61) with multidrug resistance, while 73% (391/537, 95%CI 69-76) were susceptible to first-line drugs. The analysis was limited because of unavailable treatment records and undocumented outcomes. Prospective analyses following DRSs should be considered to ensure adequate outcome data.
- Subjects :
- Botswana
Female
Follow-Up Studies
Humans
Male
Mycobacterium tuberculosis isolation & purification
Registries
Retrospective Studies
Treatment Outcome
Tuberculosis, Multidrug-Resistant microbiology
Antitubercular Agents pharmacology
Isoniazid pharmacology
Mycobacterium tuberculosis drug effects
Tuberculosis, Multidrug-Resistant drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1815-7920
- Volume :
- 18
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
- Publication Type :
- Academic Journal
- Accession number :
- 25299864
- Full Text :
- https://doi.org/10.5588/ijtld.13.0710