Hepatitis C virus inhibitory hydrolysable tannins from the fruits of Terminalia chebula.

Authors :: Ajala OS
Jukov A
Ma CM
Source :: Fitoterapia [Fitoterapia] 2014 Dec; Vol. 99, pp. 117-23. Date of Electronic Publication: 2014 Sep 28.
Publication Year :: 2014
Abstract: Two new hydrolysable tannins, chebumeinin A (1) and chebumeinin B (2), together with eight known related compounds (3-10), were isolated from the fruits of Terminalia chebula. The new compounds were structurally determined by analysis of their spectroscopic data and the known compounds characterized by comparing their spectroscopic data with literature values. All isolates were evaluated by an HCV protease inhibition assay, and some compounds were found to be potently active.<br /> (Copyright © 2014 Elsevier B.V. All rights reserved.)

Subjects :: Antiviral Agents chemistry
Hydrolyzable Tannins chemistry
Molecular Structure
Antiviral Agents pharmacology
Fruit chemistry
Hepacivirus drug effects
Hydrolyzable Tannins pharmacology
Terminalia chemistry

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