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AML cells carrying NPM1 mutation are resistant to nucleophosmin displacement from nucleoli caused by the G-quadruplex ligand TmPyP4.
- Source :
-
Cell death & disease [Cell Death Dis] 2014 Sep 25; Vol. 5, pp. e1427. Date of Electronic Publication: 2014 Sep 25. - Publication Year :
- 2014
- Subjects :
- Cell Death drug effects
Cell Line, Tumor
Humans
Leukemia, Myeloid, Acute metabolism
Nuclear Proteins metabolism
Nucleophosmin
Protein Transport drug effects
Tumor Suppressor Protein p53 genetics
Tumor Suppressor Protein p53 metabolism
Cell Nucleolus metabolism
G-Quadruplexes drug effects
Leukemia, Myeloid, Acute genetics
Mutation
Nuclear Proteins genetics
Porphyrins pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 2041-4889
- Volume :
- 5
- Database :
- MEDLINE
- Journal :
- Cell death & disease
- Publication Type :
- Editorial & Opinion
- Accession number :
- 25255220
- Full Text :
- https://doi.org/10.1038/cddis.2014.402