Back to Search
Start Over
[Clinical examination of 3 patients with delayed neuropsychiatric encephalopathy induced by carbon monoxide poisoning, who recovered from severe neurocognitive impairment by repetitive hyperbaric oxygen therapy].
- Source :
-
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica [Seishin Shinkeigaku Zasshi] 2014; Vol. 116 (8), pp. 659-69. - Publication Year :
- 2014
-
Abstract
- We performed hyperbaric oxygen (HBO) therapy for 3 patients with delayed neuropsychiatric encephalopathy induced by carbon monoxide (CO) poisoning. All patients were male and around 50 years old, and they had not received HBO therapy within 24 h after CO poisoning, even though they showed severe consciousness disturbance. In these patients, delayed neuropsychiatric encephalopathy appeared about 25 days after acute CO poisoning, and HBO therapy was initiated within 8 days after disease onset. Although the condition of 2 of the patients worsened initially, they showed significant improvement of neurocognitive impairment after 30 sessions of HBO therapy. The clinical courses of these patients suggest that the effect of HBO therapy can be evaluated after 30 sessions. To evaluate the validity of the indices of the clinical effect of HBO therapy, we performed brain magnetic resonance imaging, single photon emission computed tomography, electroencephalography (EEG), and neurocognitive tests (HDS-R, and Wechsler Adult Intelligence Scale-Revised or III). Our results showed that changes in EEG signals and neurocognitive tests were closely correlated with the patients' clinical courses.
- Subjects :
- Cognitive Dysfunction diagnosis
Cognitive Dysfunction etiology
Humans
Male
Mental Disorders etiology
Mental Disorders pathology
Mental Disorders therapy
Middle Aged
Neurotoxicity Syndromes complications
Neurotoxicity Syndromes diagnosis
Neurotoxicity Syndromes pathology
Carbon Monoxide Poisoning therapy
Cognitive Dysfunction therapy
Hyperbaric Oxygenation methods
Neurotoxicity Syndromes therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0033-2658
- Volume :
- 116
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica
- Publication Type :
- Academic Journal
- Accession number :
- 25244729