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A domino desulfurative coupling-acylation-hydration-Michael addition process for the synthesis of polysubstituted tetrahydro-4H-pyrido[1,2-a]pyrimidines.

Authors :
Yan ZF
Quan ZJ
Da YX
Zhang Z
Wang XC
Source :
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2014 Nov 14; Vol. 50 (88), pp. 13555-8.
Publication Year :
2014

Abstract

A novel method for the synthesis of the polysubstituted tetrahydro-4H-pyrido[1,2-a]pyrimidines through a domino desulfurative coupling-acylation-hydration and Michael addition sequence was established.

Details

Language :
English
ISSN :
1364-548X
Volume :
50
Issue :
88
Database :
MEDLINE
Journal :
Chemical communications (Cambridge, England)
Publication Type :
Academic Journal
Accession number :
25244523
Full Text :
https://doi.org/10.1039/c4cc05090h