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Two new guaiane sesquiterpenoids from Daphne holosericea (Diels) Hamaya.
- Source :
-
Molecules (Basel, Switzerland) [Molecules] 2014 Sep 11; Vol. 19 (9), pp. 14266-72. Date of Electronic Publication: 2014 Sep 11. - Publication Year :
- 2014
-
Abstract
- Two new sesquiterpenoids with guaiane skeletons-holosericin A (1) and holosericin B (2)-were isolated from the medicinal plant Daphne holosericea (Diels) Hamawa (Thymelaeceae). Their structures were elucidated by 1D and 2D-NMR spectroscopy, as well as HR-ESI-MS data. Compounds 1 and 2 were evaluated for inhibitory activities against acetylcholinesterase and compound 2 showed a moderate activity with 31% inhibition.
- Subjects :
- Acetylcholinesterase drug effects
Cholinesterase Inhibitors pharmacology
Daphne chemistry
Magnetic Resonance Spectroscopy
Sesquiterpenes, Guaiane isolation & purification
Sesquiterpenes, Guaiane pharmacology
Cholinesterase Inhibitors chemistry
Plant Extracts chemistry
Sesquiterpenes, Guaiane chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1420-3049
- Volume :
- 19
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Molecules (Basel, Switzerland)
- Publication Type :
- Academic Journal
- Accession number :
- 25215585
- Full Text :
- https://doi.org/10.3390/molecules190914266