Polyelectrolyte Films Boost Progenitor Cell Differentiation into Endothelium-like Monolayers.

Authors :: Berthelemy N
Kerdjoudj H
Gaucher C
Schaaf P
Stoltz JF
Lacolley P
Voegel JC
Menu P
Source :: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2008 Jul 17; Vol. 20 (14), pp. 2674-8. Date of Electronic Publication: 2008 Jun 02.
Publication Year :: 2008
Abstract: Rapid differentiation of endothelial progenitor cells (EPCs) into confluent mature endothelial cells is important in tissue engineering for the design of autologous, nonthrombotic, vascular grafts. A new method based on EPC culture on poly(sodium-4- styrene-sulfonate)/poly(allylamine hydrochloride), that is, polyelectrolyte-multilayer-coated substrates, reduces the time from two months to two weeks.<br /> (Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)

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