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Cerebellar mass as a location of acute lymphoblastic leukaemia.

Authors :
Desideri I
Canovetti S
Pesaresi I
Caniglia M
Ciancia E
Bartolozzi C
Puglioli M
Cosottini M
Source :
The neuroradiology journal [Neuroradiol J] 2014 Sep; Vol. 27 (4), pp. 439-43. Date of Electronic Publication: 2014 Aug 29.
Publication Year :
2014

Abstract

A 22-year-old man with acute lymphoblastic leukaemia was referred to our observation for headache, cervical pain and sopor. A computed tomography study revealed triventricular obstructive hydrocephalus due to a left cerebellar hyperdense mass impinging on the fourth ventricle. A magnetic resonance study demonstrated an area of hyperintensity on T2-weighted images, hypointensity on T1, restricted diffusivity and contrast enhancement involving the left hemispherical cerebellar cortex and the vermis and causing cerebellar herniation. After surgical excision of the lesion, histological examination revealed an infiltrate of lymphoblastic leukaemia with B cells. Leukaemic intracranial masses are rare. Our report describes a case presenting a cerebellar mass of leukaemic tissue characterized by high cellularity and low apparent diffusion coefficient value comparable to acute ischaemia. Therefore leukaemic intracranial mass has to be considered in the differential diagnosis of cerebellar masses.

Details

Language :
English
ISSN :
1971-4009
Volume :
27
Issue :
4
Database :
MEDLINE
Journal :
The neuroradiology journal
Publication Type :
Academic Journal
Accession number :
25196617
Full Text :
https://doi.org/10.15274/NRJ-2014-10069