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Evaluation of Shiga toxin 2e-specific chicken egg yolk immunoglobulin: production and neutralization activity.
- Source :
-
Microbiology and immunology [Microbiol Immunol] 2014 Nov; Vol. 58 (11), pp. 643-8. - Publication Year :
- 2014
-
Abstract
- Chicken egg yolk immunoglobulin (IgY) against Shiga toxin 2e (Stx2e), a major cause of swine edema disease, was prepared to evaluate its possible clinical applications. The titer of Stx2e-specific IgY in egg yolk derived from three chickens that had been immunized with an Stx2e toxoid increased 2 weeks after primary immunization and remained high until 90 days after this immunization. Anti-Stx2e IgY was found to neutralize the toxicity of Stx2e by reacting with its A and B subunits, indicating that IgY is a cost-effective agent to develop for prophylactic foods or diagnosis kits for edema disease.<br /> (© 2014 The Societies and Wiley Publishing Asia Pty Ltd.)
Details
- Language :
- English
- ISSN :
- 1348-0421
- Volume :
- 58
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Microbiology and immunology
- Publication Type :
- Academic Journal
- Accession number :
- 25175999
- Full Text :
- https://doi.org/10.1111/1348-0421.12197