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Anti-NMDA receptor encephalitis: an easily missed diagnosis in older patients.
- Source :
-
Age and ageing [Age Ageing] 2014 Sep; Vol. 43 (5), pp. 725-6. - Publication Year :
- 2014
-
Abstract
- Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an important, treatable cause of encephalitis which remains under-recognised despite a growing body of the literature [1]. It is an immune-mediated syndrome which presents with a variety of neurological symptoms including headache, fever, personality change and seizures. Most case reports to date are of young adults, it is much less frequently reported in older adults. The syndrome has been associated with ovarian teratomas. The prognosis is good with early recognition and treatment, though may relapse. We present a case of NMDA encephalitis in an elderly patient who responded well to immunosuppressive therapy.<br /> (© The Author 2014. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)
- Subjects :
- Aged
Biomarkers analysis
Encephalitis drug therapy
Encephalitis immunology
Female
Hashimoto Disease drug therapy
Hashimoto Disease immunology
Humans
Immunosuppressive Agents therapeutic use
Magnetic Resonance Imaging
Predictive Value of Tests
Treatment Outcome
Autoantibodies analysis
Diagnostic Errors
Encephalitis diagnosis
Hashimoto Disease diagnosis
Receptors, N-Methyl-D-Aspartate immunology
Subjects
Details
- Language :
- English
- ISSN :
- 1468-2834
- Volume :
- 43
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Age and ageing
- Publication Type :
- Academic Journal
- Accession number :
- 25156545
- Full Text :
- https://doi.org/10.1093/ageing/afu098