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Long-term outcome with gold thiosulphate and tiopronin in 200 rheumatoid patients.
- Source :
-
Clinical and experimental rheumatology [Clin Exp Rheumatol] 1989 Nov-Dec; Vol. 7 (6), pp. 577-81. - Publication Year :
- 1989
-
Abstract
- Two hundred rheumatoid patients were prospectively studied over a five-year period. One hundred and three received tiopronin (T) and 97 were treated with gold thiosulphate (GTS). At the end of the five-year period, similar percentages of patients dropped out because of lack of efficacy or because of major toxicities. Likewise, the percentages of patients still receiving the original drug in the two drug regimens at the 5th year of follow-up were 27.8% (GTS) vs. 25.2% (T), respectively.
- Subjects :
- Administration, Oral
Adult
Aged
Drug Administration Schedule
Drug Tolerance
Female
Follow-Up Studies
Gold Sodium Thiosulfate administration & dosage
Gold Sodium Thiosulfate adverse effects
Humans
Injections, Intramuscular
Male
Middle Aged
Prospective Studies
Recurrence
Severity of Illness Index
Therapeutic Equivalency
Tiopronin administration & dosage
Tiopronin adverse effects
Arthritis, Rheumatoid drug therapy
Gold therapeutic use
Gold Sodium Thiosulfate therapeutic use
Tiopronin therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 0392-856X
- Volume :
- 7
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Clinical and experimental rheumatology
- Publication Type :
- Academic Journal
- Accession number :
- 2515016