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Comparative analysis of gender-related differences in symptoms and referral patterns prior to initial diagnosis of urothelial carcinoma of the bladder: a prospective cohort study.
- Source :
-
Urologia internationalis [Urol Int] 2015; Vol. 94 (1), pp. 37-44. Date of Electronic Publication: 2014 Aug 13. - Publication Year :
- 2015
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Abstract
- Objective: To analyze gender-specific differences regarding clinical symptoms, referral patterns and tumor biology prior to initial diagnosis of urothelial carcinoma of the bladder (UCB).<br />Methods: A consecutive series of patients with an initial diagnosis of UCB was included. All patients completed a questionnaire on demographics, clinical symptoms and referral patterns.<br />Results: In total, 68 patients (50 men, 18 women) with newly diagnosed UCB at admission for transurethral resection of bladder tumors were recruited. Dysuria was more often observed in women (55.6 vs. 38.0%, p = 0.001). Direct consultation of the urologist was conducted by 84.0% of males and 66.7% of females (p = 0.120). One third of the women saw their general practitioner and/or gynecologist once or twice (p = 0.120) before referral to the urologist. Furthermore, women were significantly more often treated for urinary tract infections than men (61.1 vs. 20.0%, p = 0.005). Cystoscopy at first presentation to the urologist was more often performed in men than women (88.0 vs. 66.7%, p = 0.068), with a more favorable tumor detection rate at first cystoscopy in men (96.0 vs. 50.0%, p < 0.001).<br />Conclusions: Delayed referral patterns might lead to deferred diagnosis of UCB and consequently to adverse outcome. Thus, primary care physicians might consider referring patients with bladder complaints to specialized care earlier.<br /> (© 2014 S. Karger AG, Basel.)
- Subjects :
- Aged
Austria
Carcinoma diagnosis
Carcinoma surgery
Cystoscopy trends
Dysuria diagnosis
Female
General Practitioners trends
Humans
Italy
Male
Middle Aged
Predictive Value of Tests
Primary Health Care trends
Prognosis
Prospective Studies
Risk Factors
Sex Factors
Specialization trends
Surveys and Questionnaires
Time Factors
Urinary Bladder Neoplasms diagnosis
Urinary Bladder Neoplasms surgery
Urothelium surgery
Carcinoma complications
Dysuria etiology
Healthcare Disparities trends
Referral and Consultation trends
Urinary Bladder Neoplasms complications
Urothelium pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1423-0399
- Volume :
- 94
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Urologia internationalis
- Publication Type :
- Academic Journal
- Accession number :
- 25139297
- Full Text :
- https://doi.org/10.1159/000363334