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Dabigatran: patient management in specific clinical settings.
- Source :
-
Wiener klinische Wochenschrift [Wien Klin Wochenschr] 2014 Sep; Vol. 126 (17-18), pp. 503-8. Date of Electronic Publication: 2014 Aug 20. - Publication Year :
- 2014
-
Abstract
- Dabigatran, a direct thrombin inhibitor, is licensed for the prevention of venous thromboembolism after knee and hip replacement, the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation and for the treatment of acute venous thromboembolism. As dabigatran has a favourable benefit-risk profile, it is being increasingly used. Dabigatran differs from vitamin K antagonists as regards its pharmacological characteristics and its impact on certain laboratory tests, and also in the lack of a direct antagonist that can reverse dabigatran-induced anticoagulation. In emergency settings such as acute bleeding, emergency surgery, acute coronary syndrome, thrombolysis for ischaemic stroke or overdosing, specific strategies are required. A working group of experts from various disciplines has developed strategies for the management of dabigatran-treated patients in emergency settings.
- Subjects :
- Antithrombins administration & dosage
Antithrombins adverse effects
Arthroplasty, Replacement standards
Austria
Benzimidazoles standards
Dabigatran
Hemorrhage prevention & control
Humans
beta-Alanine administration & dosage
beta-Alanine adverse effects
beta-Alanine standards
Arthroplasty, Replacement adverse effects
Benzimidazoles administration & dosage
Benzimidazoles adverse effects
Hemorrhage chemically induced
Practice Guidelines as Topic
Venous Thromboembolism etiology
Venous Thromboembolism prevention & control
beta-Alanine analogs & derivatives
Subjects
Details
- Language :
- English
- ISSN :
- 1613-7671
- Volume :
- 126
- Issue :
- 17-18
- Database :
- MEDLINE
- Journal :
- Wiener klinische Wochenschrift
- Publication Type :
- Academic Journal
- Accession number :
- 25138549
- Full Text :
- https://doi.org/10.1007/s00508-014-0581-x