Back to Search
Start Over
Prostate cancer mortality outcomes and patterns of primary treatment for Aboriginal men in New South Wales, Australia.
- Source :
-
BJU international [BJU Int] 2015 Apr; Vol. 115 Suppl 5, pp. 16-23. - Publication Year :
- 2015
-
Abstract
- Objective: To compare prostate cancer mortality for Aboriginal and non-Aboriginal men and to describe prostate cancer treatments received by Aboriginal men.<br />Patients and Methods: We analysed cancer registry records for all men diagnosed with prostate cancer in New South Wales (NSW) in 2001-2007 linked to hospital inpatient episodes and deaths. More detailed information on androgen-deprivation therapy and radiotherapy was obtained from medical records for 87 NSW Aboriginal men diagnosed in 2000-2011. The main outcomes were primary treatment for, and death from, prostate cancer. Analysis included Cox proportional hazards regression and logistic regression.<br />Results: There were 259 Aboriginal men among 35,214 prostate cancer cases diagnosed in 2001-2007. Age and spread of disease at diagnosis were similar for Aboriginal and non-Aboriginal men. Prostate cancer mortality 5 years after diagnosis was higher for Aboriginal men (17.5%, 95% confidence interval (CI) 12.4-23.3) than non-Aboriginal men (11.4%, 95% CI 11.0-11.8). Aboriginal men were 49% more likely to die from prostate cancer (hazard ratio 1.49, 95% CI 1.07-1.99) after adjusting for differences in demographic factors, stage at diagnosis, health access and comorbidities. Aboriginal men were less likely to have a prostatectomy for localised or regional cancer than non-Aboriginal men (adjusted odds ratio 0.60, 95% CI 0.40-0.91). Of 87 Aboriginal men with full staging and treatment information, 60% were diagnosed with localised disease. Of these, 38% had a prostatectomy (± radiotherapy), 29% had radiotherapy only and 33% had neither.<br />Conclusion: More research is required to explain differences in treatment and mortality for Aboriginal men with prostate cancer compared with non-Aboriginal men. In the meantime, ongoing monitoring and efforts are needed to ensure Aboriginal men have equitable access to best care.<br /> (© 2014 The Authors. BJU International published by John Wiley & Sons Ltd on behalf of BJU International.)
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Humans
Male
Middle Aged
New South Wales epidemiology
Proportional Hazards Models
Prostatic Neoplasms mortality
Retrospective Studies
Treatment Outcome
White People statistics & numerical data
Young Adult
Native Hawaiian or Other Pacific Islander statistics & numerical data
Prostatic Neoplasms ethnology
Prostatic Neoplasms therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1464-410X
- Volume :
- 115 Suppl 5
- Database :
- MEDLINE
- Journal :
- BJU international
- Publication Type :
- Academic Journal
- Accession number :
- 25124107
- Full Text :
- https://doi.org/10.1111/bju.12899