Lymphodepletion followed by infusion of suicide gene-transduced donor lymphocytes to safely enhance their antitumor effect: a phase I/II study.

Authors :: Maury S
Rosenzwajg M
Redjoul R
Marcais A
Xhaard A
Cherai M
Cabanne L
Churlaud G
Suarez F
Socié G
Gregoire L
Debbache K
Bernard C
Beaumont JL
Azar N
Boyer O
Roudot-Thoraval F
Cohen JL
Cordonnier C
Lemoine FM
Klatzmann D
Source :: Leukemia [Leukemia] 2014 Dec; Vol. 28 (12), pp. 2406-10. Date of Electronic Publication: 2014 Aug 08.
Publication Year :: 2014

Subjects :: Graft vs Host Disease etiology
Humans
Lymphocyte Depletion
Lymphocytes immunology
Neoplasms complications
Neoplasms immunology
Tissue Donors
Transduction, Genetic
Treatment Outcome
Genes, Transgenic, Suicide
Genetic Therapy
Immunotherapy, Adoptive adverse effects
Lymphocytes metabolism
Neoplasms genetics
Neoplasms therapy

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