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A case series of prosthetic heart valve thrombosis-derived coronary embolism.
- Source :
-
Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir [Turk Kardiyol Dern Ars] 2014 Jul; Vol. 42 (5), pp. 467-71. - Publication Year :
- 2014
-
Abstract
- Coronary thromboembolism is a rare cause of acute coronary syndromes (ACS). The information regarding ACS in patients with prosthetic heart valves is scarce and based mainly on case reports. Although plaque rupture is the most common cause of acute myocardial infarction, coronary embolism (CE) is not a rare cause of acute myocardial infarction. There is no consensus regarding the treatment in such a situation. We present three cases of prosthetic valve thrombosis complicated with CE causing non-ST elevation ACS, who were successfully treated with thrombolytic therapy (TT). We administered low-dose (25 mg), slow-infusion (6 hours) tissue plasminogen activator (t-PA), which was shown to be safe and effective in our group in a large study. The patients benefited from TT with respect to the coronary flow, as shown by the lysis of thrombi in all three patients on coronary angiogram.
- Subjects :
- Coronary Angiography
Diagnosis, Differential
Electrocardiography
Female
Humans
Infusions, Intravenous
Male
Middle Aged
Myocardial Infarction etiology
Thrombolytic Therapy
Thrombosis diagnostic imaging
Thrombosis drug therapy
Thrombosis etiology
Tissue Plasminogen Activator administration & dosage
Heart Valve Prosthesis adverse effects
Myocardial Infarction diagnosis
Thrombosis diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1016-5169
- Volume :
- 42
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir
- Publication Type :
- Academic Journal
- Accession number :
- 25080955
- Full Text :
- https://doi.org/10.5543/tkda.2014.05031