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Diastereoselective synthesis of fused lactone-pyrrolidinones; application to a formal synthesis of (-)-salinosporamide A.
- Source :
-
Organic letters [Org Lett] 2014 Aug 15; Vol. 16 (16), pp. 4078-81. Date of Electronic Publication: 2014 Jul 28. - Publication Year :
- 2014
-
Abstract
- A mild, diastereoselective synthesis of fused lactone-pyrrolidinones using an oxidative radical cyclization is reported. The methodology is demonstrated in a formal synthesis of (-)-salinosporamide A.
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 16
- Issue :
- 16
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 25068416
- Full Text :
- https://doi.org/10.1021/ol501662t