Virus meets host microRNA: the destroyer, the booster, the hijacker.

Authors :: Guo YE
Steitz JA
Source :: Molecular and cellular biology [Mol Cell Biol] 2014 Oct; Vol. 34 (20), pp. 3780-7. Date of Electronic Publication: 2014 Jul 21.
Publication Year :: 2014
Abstract: Virus-host interactions highlight key regulatory steps in the control of gene expression. MicroRNAs (miRNAs) are small noncoding RNAs that regulate protein production via base pairing with mRNAs. Both DNA and RNA viruses have evolved mechanisms to degrade, boost, or hijack cellular miRNAs to benefit the viral life cycle. This minireview focuses on recent discoveries in virus-host miRNA interactions.<br /> (Copyright © 2014, American Society for Microbiology. All Rights Reserved.)