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A study of cardiovascular miRNA biomarkers for Kawasaki disease.

Authors :
Rowley AH
Pink AJ
Reindel R
Innocentini N
Baker SC
Shulman ST
Kim KY
Source :
The Pediatric infectious disease journal [Pediatr Infect Dis J] 2014 Dec; Vol. 33 (12), pp. 1296-9.
Publication Year :
2014

Abstract

We hypothesized that cardiovascular miRNAs might be diagnostic biomarkers for Kawasaki disease (KD). We identified dysregulated miRNAs in KD coronary arteries, and tested sera from KD patients and febrile controls for cardiovascular miRNAs using 2 methods. We did not identify cardiovascular miRNAs diagnostic for KD; our results may help guide future studies of potential miRNA biomarkers for KD.

Subjects

Subjects :
Child
Female
Humans
Infant
Infant, Newborn
Male
Biomarkers analysis
Biomarkers blood
Coronary Vessels pathology
MicroRNAs analysis
MicroRNAs blood
Mucocutaneous Lymph Node Syndrome genetics
Mucocutaneous Lymph Node Syndrome pathology

Details

Language :
English
ISSN :
1532-0987
Volume :
33
Issue :
12
Database :
MEDLINE
Journal :
The Pediatric infectious disease journal
Publication Type :
Academic Journal
Accession number :
25037038
Full Text :
https://doi.org/10.1097/INF.0000000000000449
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