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Desmodianone H and uncinanone B, potential tyrosinase inhibitors obtained from Lespedeza maximowiczii by using bioactivity-guided isolation.
- Source :
-
Bioscience, biotechnology, and biochemistry [Biosci Biotechnol Biochem] 2014; Vol. 78 (6), pp. 943-5. Date of Electronic Publication: 2014 May 28. - Publication Year :
- 2014
-
Abstract
- A new bioactive compound, namely desmodianone H(1), and another known compound uncinanone B(2) were first isolated using bioactivity-guided isolation from the leaves of Lespedeza maximowiczii and structures were elucidated by comprehensive analysis of their nuclear magnetic resonance and mass spectrometry data. Compounds 1 and 2 exhibited strong inhibitory effects on mushroom tyrosinase activity.
- Subjects :
- Agaricales enzymology
Enzyme Inhibitors chemistry
Isoflavones chemistry
Plant Leaves chemistry
Enzyme Inhibitors isolation & purification
Enzyme Inhibitors pharmacology
Isoflavones isolation & purification
Isoflavones pharmacology
Lespedeza chemistry
Monophenol Monooxygenase antagonists & inhibitors
Subjects
Details
- Language :
- English
- ISSN :
- 1347-6947
- Volume :
- 78
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Bioscience, biotechnology, and biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 25036117
- Full Text :
- https://doi.org/10.1080/09168451.2014.905180