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Inhibitory effect of (-)-epigallocatechin gallate on carcinogenesis with N-ethyl-N'-nitro-N-nitrosoguanidine in mouse duodenum.
- Source :
-
Japanese journal of cancer research : Gann [Jpn J Cancer Res] 1989 Jun; Vol. 80 (6), pp. 503-5. - Publication Year :
- 1989
-
Abstract
- (-)-Epigallocatechin gallate (EGCG) is the main polyphenolic constituent of green tea infusion and inhibits tumor promotion by teleocidin in two-stage carcinogenesis on mouse skin. In this work, EGCG was found to inhibit tumor promotion in the gastrointestinal tract in a model system of mouse duodenal carcinogenesis with N-ethyl-N'-nitro-N-nitrosoguanidine. The duodenal tumors that developed were studied stereomicroscopically and histologically.
Details
- Language :
- English
- ISSN :
- 0910-5050
- Volume :
- 80
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Japanese journal of cancer research : Gann
- Publication Type :
- Academic Journal
- Accession number :
- 2503469
- Full Text :
- https://doi.org/10.1111/j.1349-7006.1989.tb01666.x