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Retrograde flow of cadherins in collective cell migration.
- Source :
-
Nature cell biology [Nat Cell Biol] 2014 Jul; Vol. 16 (7), pp. 621-3. - Publication Year :
- 2014
-
Abstract
- Collective cell migration is characterized by the maintenance of intercellular contacts during cell movement. The maintenance of N-cadherin-based junctions during collective migration is now shown to be facilitated by their treadmilling from the cell front to the rear, followed by N-cadherin endocytosis and recycling to the leading edge.
- Subjects :
- Animals
Adherens Junctions metabolism
Cell Movement
Subjects
Details
- Language :
- English
- ISSN :
- 1476-4679
- Volume :
- 16
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Nature cell biology
- Publication Type :
- Academic Journal
- Accession number :
- 24981633
- Full Text :
- https://doi.org/10.1038/ncb2995