Back to Search Start Over

Cancer incidence in people with affective disorder: nationwide cohort study in Taiwan, 1997-2010.

Authors :
Hung YN
Yang SY
Huang MC
Lung FW
Lin SK
Chen KY
Kuo CJ
Chen YY
Source :
The British journal of psychiatry : the journal of mental science [Br J Psychiatry] 2014 Sep; Vol. 205 (3), pp. 183-8. Date of Electronic Publication: 2014 Jun 26.
Publication Year :
2014

Abstract

Background: Cancer is a serious public health problem worldwide, and its relationship with affective disorders is not clear. Aims To investigate alcohol- and tobacco-related cancer risk among patients with affective disorders in a large Taiwanese cohort.<br />Method: Records of newly admitted patients with affective disorders from January 1997 through December 2002 were retrieved from the Psychiatric Inpatient Medical Claims database in Taiwan. Cancers were stratified by site and grouped into tobacco- or alcohol-related cancers. Standardised incidence ratios (SIRs) were calculated to compare the risk of cancer between those with affective disorders and the general population.<br />Results: Some 10 207 patients with bipolar disorder and 9826 with major depression were included. The risk of cancer was higher in patients with major depression (SIR = 2.01, 95% CI 1.85-2.19) than in those with bipolar disorder (SIR 1.39, 95% CI 1.26-1.53). The elevated cancer risk among individuals ever admitted to hospital for affective disorders was more pronounced in tobacco- and/or alcohol-related cancers.<br />Conclusions: Elevated cancer risk was found in patients who had received in-patient care for affective disorders. They require holistic approaches to lifestyle behaviours and associated cancer risks.<br /> (Royal College of Psychiatrists.)

Details

Language :
English
ISSN :
1472-1465
Volume :
205
Issue :
3
Database :
MEDLINE
Journal :
The British journal of psychiatry : the journal of mental science
Publication Type :
Academic Journal
Accession number :
24970771
Full Text :
https://doi.org/10.1192/bjp.bp.114.144741