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Roussoella percutanea, a novel opportunistic pathogen causing subcutaneous mycoses.
- Source :
-
Medical mycology [Med Mycol] 2014 Oct; Vol. 52 (7), pp. 689-98. Date of Electronic Publication: 2014 Jun 25. - Publication Year :
- 2014
-
Abstract
- We report the isolation of a novel agent of subcutaneous mycosis from a 45-year-old Indian male immigrant in the United States. Phylogenetic analysis of partial small ribosomal subunit and large ribosomal subunit, internal transcribed spacer, partial translation elongation factor (TEF1), and RNA polymerase second largest subunit (rPB2) loci revealed that the strain was identical to another isolate previously reported as "Madurella mycetomatis." Both strains clustered in the order Pleosporales, nested in the family Arthopyreniaceae/Roussoellaceae. The fungus differed from known species and hence a new taxon, Roussoella percutanea, is introduced, typified by a strain that showed delayed production of pycnidial conidiomata. Antifungal susceptibility testing suggested that the new species is resistant to echinocandins and flucytosine, with variable results with azoles and amphotericin B.<br /> (© The Author 2014. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Subjects :
- Antifungal Agents pharmacology
Cluster Analysis
DNA, Fungal chemistry
DNA, Fungal genetics
DNA, Ribosomal chemistry
DNA, Ribosomal genetics
DNA, Ribosomal Spacer chemistry
DNA, Ribosomal Spacer genetics
Drug Resistance, Fungal
Emigrants and Immigrants
Humans
Male
Middle Aged
Molecular Sequence Data
Peptide Elongation Factor 1 genetics
Phylogeny
RNA Polymerase II genetics
RNA, Ribosomal, 18S genetics
RNA, Ribosomal, 28S genetics
Sequence Analysis, DNA
United States
Ascomycota classification
Ascomycota isolation & purification
Dermatomycoses microbiology
Opportunistic Infections microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 1460-2709
- Volume :
- 52
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Medical mycology
- Publication Type :
- Academic Journal
- Accession number :
- 24969729
- Full Text :
- https://doi.org/10.1093/mmy/myu035