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Ochroconis humicola coexisting with esthesioneuroblastoma: an incidental coloniser or allergen?
- Source :
-
Mycopathologia [Mycopathologia] 2014 Aug; Vol. 178 (1-2), pp. 79-83. Date of Electronic Publication: 2014 Jun 21. - Publication Year :
- 2014
-
Abstract
- Ochroconis humicola, a fish pathogen, is rarely reported to cause disease in human. We report its first isolation from nasal tissue of a human immunodeficiency virus-positive young female patient. Histopathologically, the nasal mass was diagnosed as esthesioneuroblastoma. She presented with right-sided nasal obstruction and bleeding for two and half months. Computed tomography scan showed the nasal mass filling the whole right nasal cavity, maxillary, ethmoid and sphenoid sinuses. The direct microscopy of the nasal tissue and mucin demonstrated the presence of septate hyphae. On culture, O. humicola was isolated from the same tissue and the fungus was identified by morphologic, physiologic and molecular data including sequencing of ITS and 28S rDNA regions. No antifungal was prescribed, and the whole mass was resected out by endoscopic surgery. The patient was treated further by radical radiotherapy. After 1 year of follow-up, patient is stable with no recurrence of tumour. The role of this fungus was not clear, as it may be bystander or producing allergic fungal rhinosinusitis.
- Subjects :
- Adult
Cluster Analysis
DNA, Fungal chemistry
DNA, Fungal genetics
DNA, Ribosomal chemistry
DNA, Ribosomal genetics
DNA, Ribosomal Spacer chemistry
DNA, Ribosomal Spacer genetics
Debridement
Endoscopy
Female
HIV Infections complications
Head diagnostic imaging
Histocytochemistry
Humans
Microbiological Techniques
Microscopy
Molecular Sequence Data
Mycoses surgery
Phylogeny
RNA, Ribosomal, 28S genetics
Sequence Analysis, DNA
Tomography, X-Ray Computed
Ascomycota classification
Ascomycota isolation & purification
Esthesioneuroblastoma, Olfactory complications
Mycoses diagnosis
Mycoses microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 1573-0832
- Volume :
- 178
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- Mycopathologia
- Publication Type :
- Academic Journal
- Accession number :
- 24952014
- Full Text :
- https://doi.org/10.1007/s11046-014-9759-z